An Illegal Drug Possibly Benefits For People With Multiple Sclerosis As Well As Some Thoughts Possibilities Regarding The Issue
Known all over the world for its consciousness-altering characteristics, marijuana is reported to reduce involuntary muscle contractions experienced by a lot of people with Multiple Sclerosis. Users of the renowned drug, which is derived from the flowering top of the hemp plant, cannabis sativa, have claimed that marijuana reportedly alleviated a number of their Multiple Sclerosis symptoms.
Reports that marijuana diminished Multiple Sclerosis involuntary muscle spasms prompted a small number of clinical trials conducted to determine whether a promising drug or other medical therapy might actually help sufferers.
Initial clinical research determined the function of tetrahydrocannabinol (THC), an active ingredient in marijuana, regarding the treatment of muscle spasms, tremor, and balance control in a restricted numbers of people afflicted with Multiple Sclerosis. However, the results of these studies were inconclusive, and clinical subjects noted varied side effects.
However, the researches of the effect of THC to alleviate involuntary muscle spasms reveal contrasting results. Although some sufferers reported feeling totally relaxed and became less prone to involuntary muscle spasms, the observable fact can not be specifically confirmed by objective testing. The results show that the analgesic effects of marijuana lasted a maximum of 3 hours and in increased doses corollary reactions of fatigue, thirst, lightheadedness, short-term memory loss, space and time distortions, and lack of motor control were reported.
In a study of THC concerning 8 seriously disabled men and women with advanced tremor and lack of muscle coordination, 2 subjects reported considerable improvement with tremor, which has been verified by a doctor's examination however three reported improvement that could not be verified. All of the 8 subjects that were administered THC reported experiencing a high, although two reported sensations of uneasiness and restlessness.
A limited research on the effect of marijuana also showed the drug undermines motor coordination in posture control and equilibrium of people suffering from Multiple Sclerosis and even those that did not have Multiple Sclerosis, with most subjects reporting feelings of giddiness.
The National Academy of Science/Institute of Medicine issued a report on March 17, 1999 that the medicinal uses of marijuana raised additional questions. Although the report did conclude that smoking marijuana does not have a direct part in the treatment of Multiple Sclerosis, a possibility exists that specific compounds derived from marijuana might possibly reduce some Multiple Sclerosis related symptoms, particularly those related to involuntary muscle spasms. The report has recommended that scientific and controlled studies regarding the curative potential of cannabin compounds be undertaken combined with the safe development and dependable drug delivery tools.
Medical research has tested the capability of two derivatives of marijuana called cannabin and 3 synthetic cannabins to manage unconscious muscle contractions and tremor, symptoms of the Multiple Sclerosis-like disease, in mice. These findings suggest that 4 various cannabins could in the short term relieve involuntary muscle spasms and/or tremor. Although the study suggested that derivatives of marijuana could in fact be developed for human use, the primary obstacle would be to determine the right amount of the cannabins to make them a safe and workable treatment for people with Multiple Sclerosis.
Using the results of studies accomplished so far as a starting point, the National Multiple Sclerosis Society's Medical Advisory Board states that there is presently insufficient conclusive data in order to warrant the recommendation of marijuana or its derivatives as a treatment for people afflicted with Multiple Sclerosis and that prolonged use may cause considerable serious side effects.
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